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Publications from the Biological Imaging Centre

2012

Bouet, V., Klomp, A., Freret, T., Wylezinska-Arridge, M., Lopez-Tremoleda, J., Dauphin, F., Boulouard, M., Booij, J., Gsell, W. and Reneman, L. (2012). Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment. Psychopharmacology 221, 329-339.
[ ABSTRACT ]

Klomp, A., Tremoleda, J. L., Schrantee, A., Gsell, W. and Reneman, L. (2012). The use of pharmacological-challenge fMRI in pre-clinical research: application to the 5-HT system. Journal of Visualized Experiments 3956.
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Klomp, A., Tremoleda, J. L., Wylezinska, M., Nederveen, A. J., Feenstra, M., Gsell, W. and Reneman L. (2012). Lasting effects of chronic fluoxetine treatment on the late developing rat brain: Age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. NeuroImage 59, 218-226.
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Seyfried, F., Lannoo, M., Gsell, W., Tremoleda, J. L., Bueter, M., Olbers, T., Jurowich, C., Germer, C. T. and le Roux, C. W. (2012). Roux-en-Y gastric bypass in mice-surgical technique and characterisation. Obesity Surgery, (in the Press).
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2011

Cuhlmann, S., Van der Heiden, K., Saliba, D., Tremoleda, J. L., Khalil, M., Zakkar, M., Chaudhury, H., Luong, L. A., Mason, J. C., Udalova, I., Gsell, W, Jones, H., Haskard, D. O., Krams, R. and Evans, P. C. (2011). Disturbed blood flow induces RelA expression via c-jun N-terminal kinase 1. A novel mode of NF-κB regulation that promotes arterial inflammation. Circulation Research 108, 950-959.
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Khalil, M. M., Tremoleda, J. L., Bayomy, T. B. and Gsell, W. (2011). Molecular SPECT imaging: an overview. International Journal of Molecular Imaging 2011, 796025.
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Tremoleda, J. L., Khalil, M., Gompels, L. L., Wylezinska-Arridge, M., Vincent, T. and Gsell, W. (2011). Imaging technologies for preclinical models of bone and joint disorders. EJNMMI Research 1, 11.
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2009

Chapon, C., Jackson, J. S., Aboagye, E. O., Herlihy, A. H., Jones, W. A. and Bhakoo, K. K. (2009). An in vivo multimodal imaging study using MRI and PET of stem cell transplantation after myocardial infarction in rats. Molecular Imaging and Biology 11, 31-38.
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McCabe, C., Gallagher, L., Gsell, W., Graham, D., Dominiczak, A. F. and Macrae, I. M. (2009). Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke 40, 3864-3868.
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Parkinson, J. R. C., Chaudhri, O. B., Kuo, Y.-T., Field, B. C. T., Herlihy, A. H., Dhillo, W. S., Ghatei, M. A., Bloom, S. R. and Bell, J. D. (2008). Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI). NeuroImage 44, 1022-1031.
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2008

Chapon, C., Herlihy, A. H. and Bhakoo, K. K. (2008). Assessment of myocardial infarction in mice by late gadolinium enhancement MR imaging using an inversion recovery pulse sequence at 9.4T. Journal of Cardiovascular Magnetic Resonance Imaging 10, 6.
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Santosh, C., Brennan, D., McCabe, C., Macrae, I. M., Holmes, W. M., Graham, D. I., Gallagher, L., Condon, B., Hadley, D. M., Muir, K. W. and Gsell, W. (2008). Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow & Metabolism 28, 1742-1753.
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2005

Aboagye, E. O. (2005). Positron emission tomography imaging of small animals in anticancer drug development. Molecular Imaging and Biology 7, 53-58.
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Barthel, H., Perumal, M., Latigo, J., Quinim, H., Brady, F., Luthra, J., Price, P. and Aboagye, E. O. (2005). The uptake of 3’deoxy-3’-[18F]Fluorothymidine into L5178Y tumors in vivo is dependent on thymidine kinase 1 protein and ATP levels. European Journal of Nuclear Medicine and Molecular Imaging 32, 257-263.
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2004

Bantick, R. A., Rabiner, E. A., Hirnani, E., de Vries M. H., Hume, S. P. and Grasby, P. M. (2004). Occupancy of agonist drugs at the 5-HT1A receptor. Neuropsychopharmacology 29, 847-859.
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Barthel, H., Price, P. and Aboagye, E. O. (2004). Small-animal imaging of tumour proliferation with PET. The Lancet Oncology 5, 100.

Barthel, H., Wilson, H., Collingridge, D. R., Brown, G., Osman, S., Luthra, S. K., Brady, F., Workman, P., Price, P. M. and Aboagye, E. O. (2004). In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumor hypoxia with positron emission tomography. British Journal of Cancer 90, 2232-2242.
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Bhakoo, K. K., Bell, J. D., Cox, I. J. and Taylor-Robinson, S. D. (2004). The application of magnetic resonance imaging and spectroscopy to gene therapy. Methods in Enzymology 386, 303-313.

Groot-Wassink, T., Aboagye, E. O., Wang, Y., Lemoine, N. R., Keith, W. N. and Vassaux, G. (2004). Noninvasive imaging of the transcriptional activities of human telomerase promoter fragments in mice. Cancer Research 64, 4906-4911.
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Groot-Wassink, T., Aboagye, E. O., Wang, Y., Lemoine, N. R., Reader, A. J. and Vassaux, G. (2004). Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal. Molecular Therapy 9, 436-442.
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Le Masurier, M., Houston, G., Cowen, P., Grasby, P., Sharp, T. and Hume, S. (2004). Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [11C]raclopride in striatum in vivo: a rat PET study. Synapse 51, 151-157.
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Leonardsson, G., Steel, J. H., Christian, M., Pocock, V., Milligan, S., Bell, J., So, P.-W., Medina-Gomez, G., Vidal-Puig, A., White, R. and Parker, M. G. (2004). Nuclear receptor corepressor RIP140 regulates fat accumulation. Proceedings of the National Academy of Sciences of the United States of America 101, 8437-8442.
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2003

Aboagye E. O. and Price P. (2003). Use of positron emission tomography in anticancer drug development.  Investigational New Drugs 21, 169-181.
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Barthel H., Cleji, M. C., Collingridge, D. R., Hutchinson, C. O., Osman, S., He, Q., Luthra, S. K., Brady, F., Price, P. M. and Aboagye E. O. (2003). 3'Deoxy-3'-[18F]Fluorothymidine as a new marker for monitoring response to anti-proliferative therapy in vivo with positron emission tomography. Cancer Research 63, 3791-3798.
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Collingridge, D. R., Glaser, M., Osman, S., Barthel, H., Hutchinson, O.C., Luthra, S.J., Brady, F., Bouchier-Hayes, L., Martin, S. J., Workman, P., Price, P. and Aboagye, E. O. (2003). In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope. British Journal of Cancer 89, 1327-1333.
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Hirnani, E., Sharp, T., Sprakes, M., Grasby, P. and Hume S. (2003). Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: Small animal PET and gene expression studies. Synapse 50, 251-260.
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2002

Collingridge, D. R., Carroll, V. A., Glaser, M., Aboagye, E. O., Osman, S., Hutchinson, O. C., Barthel, H., Luthra, S. K., Brady, F., Bicknell, R., Price, P. and Harris, A. L. (2002). [124I]Iodinated-VG76e: a novel tracer for imaging Vascular Endothelial Growth Factor in vivo using positron emission tomography. Cancer Research 62, 5912-5919.
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Groot-Wassink, T., Aboagye, E. O., Glaser, M., Lemoine, N. and Vassaux, G. (2002). Adenovirus biodistribution and non-invasive imaging of gene expression in vivo by positron emission tomography using the human sodium/iodide symporter as a reporter gene. Human Gene Therapy 13, 1723-1735.
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Hume, S. P. and Myers, R. (2002). Dedicated small animal scanners: a new tool for drug development? Current Pharmaceutical Design 8, 1497-1511.
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Myers, R. and Hume, S. (2002). Small animal PET. Neuropsychopharmacology 12, 545-555.
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2001

Osman, S., Rowlinson-Busza, G., Luthra, S. K., Aboagye, E. O., Brown, G. D., Brady, F., Gamage, S. A., Denny, W. A., Baguley, B. C. and Price, P. (2001). Comparative biodistribution and metabolism of carbon-11 labelled of N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide, DACA, and 'minimal' DNA-intercalating analogues. Cancer Research 61, 2935-2944.
[ ABSTRACT ] [ FULL TEXT ]

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