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<title>Latest publications from   Gene Regulation and Chromatin Research Group</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
<description>MRC Clinical Sciences Centre</description>
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<title>Clinical Sciences Centre</title>
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<title>Thu, 8 Jul 2010</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Liber, D., Domaschenz, R., Holmqvist, P.-H., Mazzarella, L., Georgiou, A., Leleu, M., Fisher, A. G., Labosky, P. A., Dillon, N. (2010). Epigenetic priming of a pre-B cell-specific enhancer through binding of sox2 and foxd3 at the ESC stage. &lt;em&gt;Cell Stem Cell&lt;/em&gt; 7, 114&amp;ndash;126. &lt;a href="http://dx.doi.org/10.1016/j.stem.2010.05.020" target="_blank"&gt;Abstract&lt;/a&gt;</description>
<pubDate>2010-07-08 14:56:57 GMT</pubDate>
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<title>Tue, 20 Jan 2009</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Szutorisz, H., Georgiou, A., Tora, L. &amp;amp; Dillon, N. (2006). The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. &lt;em&gt;Cell&lt;/em&gt; 127, 1375-1388. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/17190601" target="_blank"&gt;Abstract&lt;/a&gt;</description>
<pubDate>2009-01-20 14:49:03 GMT</pubDate>
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<title>Thu, 15 Jan 2009</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Szutorisz, H., Canzonetta, C., Georgiou, A., Chow, C.-M., Tora, L. &amp;amp; Dillon, N. (2005). Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. &lt;em&gt;Molecular and Cellular Biology&lt;/em&gt; 25, 1804-1820. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/15713636" target="_blank"&gt;Abstract&lt;/a&gt; | &lt;a href="http://mcb.asm.org/cgi/content/full/25/5/1804?view=long&amp;pmid=15713636" target="_blank"&gt;Full text&lt;/a&gt;</description>
<pubDate>2009-01-15 11:20:21 GMT</pubDate>
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<title>Thu, 15 Jan 2009</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Chow, C.-M., Georgiou, A., Szutorisz, H., Maia e Silva, A., Pombo, A., Barahona, I., Dargelos, E., Canzonetta, C. &amp;amp; Dillon, N. (2005). Variant histone H3.3 marks promotors of transcriptionally active genes during mammalian cell division. &lt;em&gt;EMBO Reports&lt;/em&gt; 6, 354-360. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/15776021" target="_blank"&gt;Abstract&lt;/a&gt; | &lt;a href="http://www.nature.com/embor/journal/v6/n4/full/7400366.html" target="_blank"&gt;Full text&lt;/a&gt;</description>
<pubDate>2009-01-15 11:20:05 GMT</pubDate>
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<title>Thu, 15 Jan 2009</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Sabattini, P., Canzonetta, C., Sjoberg, M., Nikic, S., Georgiou, A., Kemball-Cook, G., Auner, H. W. &amp;amp; Dillon, N. (2007). A novel role for Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells. &lt;em&gt;The EMBO Journal&lt;/em&gt; 26, 4657-4669. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/17948062" target="_blank"&gt;Abstract&lt;/a&gt; | &lt;a href="http://www.nature.com/emboj/journal/v26/n22/abs/7601875a.html" target="_blank"&gt;Full text&lt;/a&gt;</description>
<pubDate>2009-01-15 11:19:47 GMT</pubDate>
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<title>Thu, 15 Jan 2009</title>
<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Dillon, N. (2008). The impact of gene location in the nucleus on transcriptional regulation. &lt;em&gt;Developmental Cell&lt;/em&gt; 15, 182-186. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/18694558" target="_blank"&gt;Abstract&lt;/a&gt;</description>
<pubDate>2009-01-15 11:19:39 GMT</pubDate>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Sabbattini, P., Georgiou, A. Sinclair, C. &amp;amp; Dillon, N. (1999). Analysis of mice with single copies and multiple copies of transgenes reveals a novel arrangement for the &lt;img src="/SpecialCharacters/Lambda000000.gif"width="5"height="8"&gt;&lt;em&gt;5-V&lt;/em&gt;&lt;sub&gt;preB1&lt;/sub&gt; locus control region. &lt;em&gt;Molecular and Cellular Biology&lt;/em&gt; 19, 671-679. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/9858590" target="_blank"&gt;Abstract&lt;/a&gt; | &lt;a href="http://mcb.asm.org/cgi/content/full/19/1/671?view=long&amp;pmid=9858590" target="_blank"&gt;Full text&lt;/a&gt;</description>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Lundgren, M., Chow, C. M. Sabbattini, P., Georgiou, A., Minaee, S. &amp;amp; Dillon, N. (2000). Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene. &lt;em&gt;Cell&lt;/em&gt; 103, 733-743. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/11114330" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Dillon, N. &amp;amp; Sabbattini, P. (2000). Functional gene expression domains: defining the functional unit of eukaryotic gene regulation. &lt;em&gt;BioEssays&lt;/em&gt; 22, 657-665. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/10878578" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Sabbattini, P., Lundgren, M., Georgiou, A., Chow, C.-M., Warnes, G. &amp;amp; Dillon, N. (2001). Binding of Ikaros to the &lt;img src="/SpecialCharacters/Lambda000000.gif"width="5"height="8"&gt;5 promoter silences transcription through a mechanism that does not require heterochromatin formation. &lt;em&gt;The EMBO Journal&lt;/em&gt; 20, 2812-2822. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/11387214" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Dillon, N. &amp;amp; Festenstein, R. (2002). Unravelling heterochromatin: competition between positive and negative factors regulates the accessibility of chromatin. &lt;em&gt;Trends in Genetics&lt;/em&gt; 18, 252-258. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/14523423" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Dillon, N. (2003). Gene autonomy: position effects continue to raise questions about the physical structure of the particulate mendelian gene. &lt;em&gt;Nature&lt;/em&gt; 425, 457. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/14523423" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<link>http://www.csc.mrc.ac.uk/Research/Groups/EDC/GeneRegulationChromatin/Publications/</link>
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<description>Tak&amp;aacute;cs, K., Du Roure, C., Nabarro, S., Dillon, N., McVey, J. H., Webster, Z., MacNeil, A., Bart&amp;oacute;k, I., Higgins, C., Gray, D., Merkenschlager, M. &amp;amp; Fisher, A. G. (2004). The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes. &lt;em&gt;Proceedings of the National Academy of Sciences of the United States of America&lt;/em&gt; 101, 16298-16303. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/15520381" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Szutorisz, H., Dillon, N. &amp;amp; Tora, L. (2005). The role of enhancers as centres for general transcription factor recruitment. &lt;em&gt;Trends in Biochemical Sciences&lt;/em&gt; 30, 593-599. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/16126390" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Szutorisz, H. &amp;amp; Dillon, N. (2005). The epigenetic basis fro embryonic stem cell pluripotency &lt;em&gt;BioEssays&lt;/em&gt; 27, 1286-1293. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/16299767" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Sabbattini, P. &amp;amp; Dillon, N. (2005). The &lt;img src="/SpecialCharacters/Lambda000000.gif"width="5"height="8"&gt;-&lt;em&gt;VpreB1&lt;/em&gt; locus&amp;#8212;a model system for studying gene regulation during early B cell development. &lt;em&gt;Seminars in Immunology&lt;/em&gt; 17, 121-127. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/15737573" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Minaee, S., Farmer, D., Georgiou, A., Sabbattini, P., Webster, Z., Chow, C.-m. &amp;amp; Dillon, N. (2005). Mapping and functional analysis of regulatory sequences in the mouse &lt;img src="/SpecialCharacters/Lambda000000.gif"width="5"height="8"&gt;5-VpreB1 domain. &lt;em&gt;Molecular Immunology&lt;/em&gt; 42, 1283-1292. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/15950724" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Dillon, N. (2006). Gene regulation and large-scale chromatin organization in the nucleus. &lt;em&gt;Chromosome Research&lt;/em&gt; 14, 117-126. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/16506101" target="_blank"&gt;Abstract&lt;/a&gt; | &lt;a href="http://www.springerlink.com/media/g2e72bpvwn4vrlcynwul/contributions/4/2/0/q/420q755r67h62144.pdf" target="_blank"&gt;Full text&lt;/a&gt;</description>
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<description>Thompson, E. C., Cobb, B. S., Sabbattini, P., Meixlsperger, S., Parelho, V., Liberg, D., Taylor, B., Dillon, N., Georgopoulos, K., Jumaa, H., Smale, S. T., Fisher, A. G. &amp;amp; Merkenschlager, M. (2007). Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. &lt;em&gt;Immunity&lt;/em&gt; 26, 335-344. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/17363301" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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<description>Parelho, V., Hadjur, S., Spivakov, M., Leleu, M., Sauer, S., Gregson, H. C., Jarmuz, A., Canzonetta, C., Webster, Z., Nesterova, T., Cobb, B. S., Yokomori, K., Dillon, N., Aragon, L., Fisher, A. G. &amp;amp; Merkenschlager, M. (2008). Cohesins functionally associate with CTCF on mammalian chromosome arms. &lt;em&gt;Cell&lt;/em&gt; 132, 422-433. &lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/18237772" target="_blank"&gt;Abstract&lt;/a&gt;</description>
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